Schedule
for Beijing Symposium on Protein Folding,
Function and Dynamics
Monday July 4
08:30-08:40 Welcome Remarks
Session
I Chairman: Feng Gai£¨UPenn£©
08:40-09:40 Michael Levitt£¨Stanford University£©
Using Toys Models to Explore the Protein Universe
09:40-10:15 Ruhong Zhou£¨IBM/Columbia U£©
Dewetting
Transition and Hydrophobic Collapse in Protein Aggregates
10:15-10:35 Tea Break
10:35-11:10 Martin Gruebele£¨UIUC£©
Downhill Folding on Rough Free Energy Surfaces: physics and evolution at work
11:10-11:45 Hiroshi Kihara (Kansai Medical U)
Alpha-helix-rich folding core of beta-sheeted proteins
12:00-13:30 Lunch
Session II Chairman: Valerie Daggett£¨University
of Washington£©
13:30-14:05 Huanxiang Zhou(Florida State University)
Electrostatic Interactions
in Unfolded, Folded, Complexed, and Transition States of Proteins
14:05-14:40 Jianpeng Ma (Baylor/Rice)
New Methods for Simulating Protein Dynamics at Multi-resolution and
Multi-length Scales
14:40-15:15 Hue Sun Chan£¨Toronto U£©
Desolvation is a Likely Origin of Robust Enthalpic Barriers to Cooperative
Protein Folding
15:15-15:50 Jin Wang (SUNY Stony Brook)
Diffusion Dynamics of Protein Folding
15:50-16:10 Tea Break
Session III Chairman: Yunyu Shi £¨USTC£©
16:10-16:45 Junmei Zhou £¨Inst. Of Biophysics, CAS£©
Molecular Chaperone Function of Escherichia coli Trigger Factor
16:45-17:20 Yi Liang£¨Wuhan University£©
Mixed Macromolecular Crowding Accelerates the Oxidative Refolding of Reduced,
Denatured Lysozyme: Implications for Protein Folding in Intracellular Environments
17:20-17:55 Changwen Jin (PKU)
Solution Structures and Functional Insights of an Arsenate Reductase from Bacillus
subtilis: Reversible Conformational Switch Associates with the Arsenate Reduction
Tuesday, July 5
Session I Chairman: Jeff Saven (UPenn)
08:30-09:30 Alan Fersht£¨Cambridge University£©
How Small Proteins Fold
09:30-10:05 Yunyu Shi £¨USTC£©
Protein
structure and protein-protein interaction studied by NMR
10:05-10:25 Tea Break
10:25-11:00 Valerie Daggett£¨University of Washington£©
Protein Unfolding and Refolding at Atomic Resolution
11:00-11:35 Yong Duan £¨UC Davis£©
Folding and aggregation: A physics-based all-atom modeling
11:35-11:50 Sarah Perrett £¨Inst. Of Biophysics, CAS£©
Factors
influencing the function, folding and fibril formation of the yeast prion protein
ure2
12:00-13:30 Lunch
Session II Chairman: Chih-Chen Wang£¨Inst. Of Biophysics, CAS£©
13:30-14:05 Feng Gai£¨UPenn£©
Understanding the Folding Mechanism of b-Hairpins
14:05-14:40 Yongzhang Luo£¨Tsinghua U£©
Refolding of Proteins from in vitro to in vivo
14:40-15:15 Zengyi Chang (PKU)
Immediate
response to stress conditions for the structure and activity of molecular Chaperones
15:15-15:50 Chi-Ming Chen (National Taiwan Normal University, Taiwan)
Structure Prediction and Folding Dynamics of Bacteriorhodopsin
15:50-16:10 Tea Break
Session III Chairman: Luhua Lai£¨PKU£©
16:10-16:25 Yuguang Mu (Nanyang Technological University, Singapore; ShanDong
University,China)
Intermediate
states of forming binding protein WW domain: explored by replica-exchange simulation
16:25-16:40 Fan Jiang (Institute of Physics, CAS)
Scaling laws in folding of native protein structures
16:40-16:55 Bin Lai (Stony Brook University)
Translocation of Diphtheria Toxin T Domain-Induced Translocation of
the Diphtheria Toxin Catalytic Domain (A Chain) Across Membranes: Role of Changes
in Protein Folding/Unfolding
16:55-17:10 Rongzheng Wan (Shanghai Institute of Applied Physics, CAS)
Controllable water channel gating of nanometer dimensions
17:10-17:25 Ming Lei (Beijing University of Chemical Technology)
Role of conformational change in initial partial disrupted path of V14N/V16E
mutant of transthyretin: Insights from molecular dynamic simulation
17:25-17:40 Xiaohong Shi (Huazhong University of Sciences and Technology)
A Finding Maximal Clique Algorithm for predicting Loop of Protein Structure
17:40-17:55 Ying-Chieh Sun(National Taiwan Normal University, Taiwan)
Examination of Several Factors Affecting Folding of Short Helical Peptides
Using Molecular Dynamics Simulation
Wednesday July 6
Session I Chairman: Zengyi Chang£¨PKU£©
08:30-09:30 Chih-Chen Wang£¨Inst. Of Biophysics, CAS£©
Dimerization and chaperone activity of thiol-protein oxidoreductases
09:30-10:05 Yawen Bai £¨NIH£©
Hidden Intermediates at Atomic Resolution: Implications for Protein
Folding
10:05-10:25 Tea Break
10:25-11:00 Wei Wang (Nanjing U)
Folding of small proteins using simplified Go-model and all-atom model
11:00-11:35 Emily Ching£¨Chinese U of HK£©
Characteristic patterns in amino acid sequences and their use in the
prediction of protein structures
11:35-11:50 Aoneng Cao£¨PKU£©
Mechanism
of the folding and chaperone-like activity of the small heat shock protein rom
Methanococcus jannaschii
12:00-13:30 Lunch
13:30-15:00 Poster Session
Tuesday July 7
Session I Chairman: Ruhong Zhou£¨IBM/Columbia
U£©
08:30-09:30 William Degrado£¨UPenn£©
De Novo design of Catalytic Proteins
09:30-10:05 Chao Tang (UCSF/PKU)
Flexibility of secondary structures from database analysis
10:05-10:25 Tea Break
10:25-11:00 Yaoqi Zhou (SUNY Buffalo)
Molecular mechanism of binding cooperativity in a dimeric hemoglobin
11:00-11:35 Ray Luo (UC Irvine)
Unfolding and refolding of p53 cancer and suppressor mutations
11:35-11:50 Jingyuan Li £¨Zhejiang University£©
Hydration and Dewetting near Graphite-CH3 and Graphite-COOH Plates
12:00-13:30 Lunch
Session II Chairman: Chao Tang£¨UCSF/PKU£©
13:30-14:05 Jeff Saven (UPenn)
Methods for engineering protein structure and function with computational
protein design
14:05-14:40 Chen Zeng (George Washington U)
Application of Generic Sidechains and Softmodes in Protein Design
14:40-15:15 Hong Qian (U. of Washington)
Dynamics on Energy Landscapes: From Protein Folding Pathways to Open-systems
Thermodynamics of Kinetic Proofreading
15:15-15:50 Luhua Lai £¨PKU£©
Functional Protein Design Targeting Protein-Protein Interface